Toxicology
Human
Fever
A man had an influenza-induced fever of 104oF and recovered quickly. The first sample obtained at 18 days after the fever had an approximate 50% DFI and then improved (Figure 4 ) (Evenson et al. 2000).

Figure 4. The control (pre-fever) sample is in the upper left-hand corner. Note that the 25 day sample post-fever contained a significant number of sperm with an increased susceptibility to DNA denaturation. By 53 and 66 days post-fever, the DFI values have returned to pre-fever values (Evenson et al. 2000).